Quantikine Immunoassay Control Set 841 for Human CHI3L1 (1 EA)
货号：
QC63 基本售价：
1774.7 元 规格：
1 Each
产品信息
概述| 货号 | QC63 |
| 简介 | For use with catalog number DC3L10 |
| 别名 | AW208766; Brp39; CHI3L1; gp39; HCgp39; YKL-40 |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 1116 (Human); 12654 (Mouse) |
| 背景 | Chitinase 3-like 1 (CHI3L1), also called BRP39 in mouse or YKL-40 in humans, is a 39 kDa glycoprotein member of the glycosyl hydrolase 18 family although it does not show chitotriosidase activity. CHI3L1 is expressed by articular chondrocytes, synovial cells, activated monocyte-derived macrophages, neutrophils, endothelial cells, vascular smooth muscle cells, and some cancer cells. CHI3L1 binds to chitin and heparins, and it enhances cell adhesion, proliferation and tumor angiogenesis. Circulating CHI3L1 is elevated during inflammation and connective tissue remodeling such as arthritis, chronic obstructive pulmonary disease, diabetes, cardiovascular disease, inflammatory bowel disease, and liver cirrhosis. It is frequently upregulated in glioblastoma, myxoid chondrosarcoma, melanoma and carcinomas of the breast, thyroid, colon, lung, kidney, and ovary. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Cancer Biomarkers
- Extracellular Matrix Molecules
- Glycobiology-related Enzymes
- Lysosomal Enzymes
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