Quantikine Immunoassay Control Set 811 for Human Proinsulin (1 EA)
货号：
QC148 基本售价：
1774.7 元 规格：
1 Each
产品信息
概述| 货号 | QC148 |
| 简介 | For use with catalog number DPINS0 |
| 别名 | IDDM2; ILPR; insulin; IRDN; MODY10; proinsulin |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 3630 (Human); 16333 (Mouse) |
| 背景 | Insulin is a peptide hormone that is critical for glucose homeostasis. The mature Insulin peptide is derived from Proinsulin, which includes the Insulin A and B chains connected by a peptide fragment (Insulin C-peptide). Proinsulin is processed within the endoplasmic reticulum of pancreatic beta cells into equimolar ratios of mature Insulin and Insulin C-peptide. Proinsulin binds the Insulin Receptor A isoform (IR-A) with high affinity resulting in cell proliferation and migration. It has low binding affinity for the Insulin Receptor B isoform (IR-B) and the Insulin-like Growth Factor I Receptor (IGF R1). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Diabetes
- Glucose Homeostasis
- Growth Hormone/IGF-I Axis
- ICC / IHC Images: Proinsulin
- Nutrition and Appetite
- Pancreatic Endoderm
- Pancreatic Endoderm Cell Markers
- Protein/Peptide Hormones and Regulators
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