| 货号 | MS-1402-P1ABX |
| 描述 | DNA polymerase Β comprises an amino-terminal 8-kDa domain and a carboxy-terminal 31-kDa domain. The N-terminal ssDNA binding domain has a deoxyribose phosphodiesterase activity while the C-terminal domain has a nucleotidyltransferase activity. Mammalian DNA polymerase Β, a DNA repair polymerase, is constitutively expressed in cultured cells, but treatment of cells with the DNA-alkylating agents such as N-methyl-N-nitro-N-nitrosoguanidine (MNNG) or methyl methanesulfonate up-regulates β-pol level. DNA polymerase Β fills single nucleotide gaps in DNA produced by the base excision repair pathway of mammalian cells. Epitope: Not determined Cellular Localization:Nuclear Note: USA: RUO; Intl: RUO |
| 克隆号 | 61 |
| 同种亚型 | IgG2a |
| 反应种属 | Human. Others not known. |
| 来源宿主 | Mouse |
| 使用方法 |
|
| 供应商 | Labvision |
| 免疫原 | DNA polymerase β protein |
| 存放说明 | 零下20摄氏度 |
| 浓度 | 1mg/mL |
| 计算分子量 | 39kDa |
| 参考文献 | 1. Srivastava DK, et. al. Journal of Biological Chemistry, 1995, 270(27):16402-8. 2. Beard WA Wilson SH. Methods in Enzymology, 1995, 262:98-107. 3. Husain I et al. Nucleic Acids Research, 1995, 23(9):1597-603. |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |