货号 | RB-1516-P1 |
描述 | Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species. Epitope:N-terminal Cellular Localization:Nuclear Note: USA: RUO; Intl: RUO |
同种亚型 | IgG |
反应种属 | Human, Mouse and Rat. Others not known. |
来源宿主 | Rabbit |
使用方法 |
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供应商 | Labvision |
免疫原 | A synthetic peptide for the N-terminal region of human PARP |
存放说明 | 2-8摄氏度 |
浓度 | 1mg/mL |
计算分子量 | 116kDa |
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