| 货号 | MS-669-B0 |
| 描述 | DNA polymerase Β comprises an amino-terminal 8-kDa domain and a carboxy-terminal 31-kDa domain. The N-terminal ssDNA binding domain has a deoxyribose phosphodiesterase activity while the C-terminal domain has a nucleotidyltransferase activity. Mammalian DNA polymerase Β, a DNA repair polymerase, is constitutively expressed in cultured cells, but treatment of cells with the DNA-alkylating agents such as N-methyl-N-nitro-N-nitrosoguanidine (MNNG) or methyl methanesulfonate up-regulates β-pol level. DNA polymerase Β fills single nucleotide gaps in DNA produced by the base excision repair pathway of mammalian cells. Species Reactivity: Human, Cow, Mouse, Rat, Hamster and Xenopus. Others not known. Epitope: Not determined Note: USA: RUO; Intl: RUO |
| 克隆号 | 18S |
| 同种亚型 | IgG1 |
| 反应种属 | Human, Cow, Mouse, Rat, Hamster and Xenopus. Others not known. |
| 来源宿主 | Mouse |
| 使用方法 |
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| 供应商 | Labvision |
| 免疫原 | Rat DNA polymerase β protein |
| 存放说明 | 2-8摄氏度 |
| 浓度 | 200μg/mL |
| 计算分子量 | 39 kDa |
| 参考文献 | 1. Srivastava DK, et. al. Journal of Biological Chemistry, 1995, 270(27):16402-8. |
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