| 货号 | AGR-003-50ul |
| 描述 | Each antibody ordered from Alomone Labs is supplied with its corresponding control peptide (antigen), free of charge. A Rabbit Polyclonal Antibody to Glycine Receptor α3 |
| 反应种属 | H, M, R |
| 应用 | IH, WB |
| 供应商 | Alomone |
| 背景 | Glycine is a major neurotransmitter in the mammalian central nervous system.1 The glycine receptor is a ligand gated Cl- channel, mediating synaptic inhibition in the spinal cord, retina and regions of the brain.2 The glycine receptor is a pentamer consisting of α and β subunits. To date there are four known α-subunit isoforms (α1- α4) encoded by different genes.2-4 In humans, two alternative splice variants of the glycine receptor α3 have been described: α3L, and α3K where the α3L splice variant bears an additional segment of 15 amino acids within the long cytoplasmic TM3-4 loop. These variants differ in their desensitization kinetics.3 |
| 运输条件 | Ambient |
| 存放说明 | -20 |
| 纯度 | Affinity purified on immobilized antigen. |
| 参考文献 | 1.Becker, C.M.(1995)The Neuroscientist 1,130. 2.Gisselmann, G.et al.(2002)Eur. J. Neurosci. 16,69. 3.Nikolic, Z.et al.(1998)J. Biol. Chem. 273,19708. 4.Breitinger, H.G.et al.(2002)J.Neurochem.83,30. |
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