| 货号 | APR-021-25ul |
| 描述 | Each antibody ordered from Alomone Labs is supplied with its corresponding control peptide (antigen), free of charge. A Rabbit Polyclonal Antibody to P2Y1 Receptor |
| 反应种属 | H, M, R |
| 应用 | IC, IFC, IH, LCI, WB |
| 供应商 | Alomone |
| 背景 | TheP2Y receptors belong to the G-protein coupled receptors superfamily. P2Y receptors mediate the actions of the extracellular nucleotides (ATP, ADP, UTP and UDP) and regulate several physiologic responses, among them, cardiac function, platelet aggregation and SMC proliferation.1 The mammalian P2Y family currently includes eight functional receptors; P2Y1,P2Y2,P2Y4,P2Y6,P2Y11,P2Y12,P2Y13, and the UDP-glucose receptor, now renamed P2Y14.2-4 P2Y1 receptor is abundantly expressed in a number of tissues. In platelets, P2Y1 receptor is co-expressed with P2Y12 receptor, responsible for the initial shape change, aggregation, and rise in intracellular Ca2+ upon activation in response to ADP.5 |
| 运输条件 | Ambient |
| 存放说明 | -20 |
| 纯度 | Affinity purified on immobilized antigen. |
| 参考文献 | 1.Wang, L. et al. (2002) J. Cardiovas. Pharmacol.40,841. 2.Queiroz, G. et al. (2003) J. Pharmacol. Exp. Ther.307,809. 3.Ralevic, V. and Burnstock, G. (1998)Pharmacol. Rev.50,413. 4.Abbracchio, M.P. et al. (2003) Trends. Pharmacol. Sci.24,52. 5.Jin, J. et al. (1998) J. Biol. Chem.273,2030. |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |