| 货号 | APR-011-25ul |
| 描述 | Each antibody ordered from Alomone Labs is supplied with its corresponding control peptide (antigen), free of charge. A Rabbit Polyclonal Antibody to P2Y6 Receptor |
| 反应种属 | H, M, R |
| 应用 | IC, IFC, IH, IP, WB |
| 供应商 | Alomone |
| 背景 | The nucleotide receptor P2Y6 binds UDP, and is a member of the G-protein coupled receptor superfamily.1,3 P2Y6 agonists induce an inositol phosphate/Ca2+ response that is insensitive to pertussis toxin inhibition. P2Y6 is coupled to phospholipase C via Gq, and is also coupled to inhibition of N-type Ca2+ and M-type K+ channels.1,2 P2Y6 mRNA is expressed in various rat tissues, including lung, stomach, intestine, spleen, heart, and aorta. P2Y6 was reported to mediate contractions in human cerebral arteries.4 |
| 运输条件 | Ambient |
| 存放说明 | -20 |
| 纯度 | Affinity purified on immobilized antigen. |
| 参考文献 | 1.Communi, D.et al.(2000)Cell Signal.12,351. 2. Filippov, A.K. et al.(1999)Br. J. Pharmacol. 270,26152. 3.Chang, K.et al.(1995)J. Biol. Chem.270,26152. 4.Malmsjo, M.et al.(2003)B.M.C. Pharmacol.3,4. |
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