| 货号 | APR-004-25ul |
| 描述 | Each antibody ordered from Alomone Labs is supplied with its corresponding control peptide (antigen), free of charge. A Rabbit Polyclonal Antibody to P2X7 Receptor |
| 反应种属 | H, M, R |
| 应用 | IC, IFC, IH, IP, WB |
| 供应商 | Alomone |
| 背景 | The P2X7 receptor is a member of the ionotropic P2X receptor family that is activated by ATP. To date, this family is composed of seven receptor subtypes, named P2X1-P2X7, all of which have been cloned. The various P2X receptors show distinct expression patterns. P2X1-6 receptors have been found in the central and peripheral nervous system, while the P2X7 receptor is found in cells of the immune system, particularly in antigen-presenting cells, and microglia. The P2X7 receptor mediates the release of proinflamatory cytokines and stimulation of transcription factors and may also play an important role in apoptosis.1-3 |
| 运输条件 | Ambient |
| 存放说明 | -20 |
| 纯度 | Affinity purified on immobilized antigen. |
| 参考文献 | 1.Ding, Y.et al.(2000)J. Auton. Nerv. Syst. 81,289. 2.Kim, M.et al.(2001)EMBO J. 20,6347. 3.Chizh, B.A. and Illes, P.(2001)Pharmacol. Rev. 53,553. |
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