货号 | ACC-034-25ul |
描述 | Each antibody ordered from Alomone Labs is supplied with its corresponding control peptide (antigen), free of charge. A Rabbit Polyclonal Antibody to TRPV4 Channel |
反应种属 | H, M, R |
应用 | IC, IFC, IH, IP, WB |
供应商 | Alomone |
背景 | TRP channels are a large family (about 28 genes) of plasma membrane, non-selective cationic channels that are either specifically or ubiquitously expressed in excitable and non-excitable cells.1 According to IUPHAR the TRP family comprises of three main subfamilies on the basis of sequence homology; TRPC,TRPMandTRPV (to date, three extra subfamilies are considered to belong to the TRP family; the TRPA,TRPML, and TRPP).1-4 The TRPV subfamily consists of six members, TRPV1-6.5 TRPV4 (also named OTRPC4) is activated under hypotonic conditions and serves as an osmoreceptor. TRPV4 is expressed in brain, liver, kidney, heart, testis and salivary gland.6 |
运输条件 | Ambient |
存放说明 | -20 |
纯度 | Affinity purified on immobilized antigen. |
参考文献 | 1.Montell, C.et al. (2002) Mol. Cell.9, 229. 2.Clapham, D.E. (2003) Nature426, 517. 3.Moran, M.M.et al. (2004) Curr.Opin.Neurobiol.14, 362. 4.Clapham, D.E.et al. (2003) Pharmacol. Rev.55, 591. 5.Gunthorpe, M.J.et al. (2002) Trends. Pharmacol. Sci.23, 183. 6.Peng, J.B.et al. (2003) J. Physiol.551.3, 729. |
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