Mouse LIF Biotinylated Affinity Purified PAb (50 UG)
货号：
BAF449 基本售价：
5958.6 元 规格：
-
产品信息
概述| 货号 | BAF449 |
| 别名 | CDF; D factor; DIA; differentiation inhibitory activity; differentiation stimulating factor; Differentiation-stimulating factor; Emfilermin; HILDAcholinergic differentiation factor; leukemia inhibitory factor (cholinergic differentiation factor); leukemia inhibitory factor; Melanoma-derived LPL inhibitor; MLPLI |
全称 | Leukemia Inhibitory Factor | | 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL)
|
| 目标/特异性 | Detects mouse LIF in Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human LIF (under non-reducing conditions) is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL
|
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 3976 (Human); 16878 (Mouse); 403449 (Canine) |
| 应用文献 |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Adenosine A2B receptor-mediated leukemia inhibitory factor release from astrocytes protects cortical neurons against excitotoxicity.
Authors: Moidunny S, Vinet J
J Neuroinflammation, 2012;9(1):198.
Species: Mouse
Sample Type: Cell Culture Supernates
Application: ELISA Development |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant mouse LIF |
| 生物活性 | Mouse |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Based on its helical structure, LIF (Leukemia Inhibitory Factor) is considered a member of the Interleukin-6 family of cytokines. Functionally, it has been implicated in a many physiological processes including development, hematopoiesis, bone metabolism, and inflammation. Some cell types known to express LIF include activated T cells, monocytes, astrocytes, osteoblasts, keratinocytes, regenerating skeletal muscle, mast cells, and fibroblasts. The activities of LIF are mediated through a high-affinity heterodimeric receptor complex consisting of two membrane glycoproteins: an alpha subunit (LIF R alpha, also known as LIF R beta and CD118) that binds LIF with low affinity and the 130 kDa (gp130) subunit that does not bind LIF by itself, but is required for high-affinity binding of LIF by the complex. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Cytokines and Receptors in Allergy and Asthma
- Diabetes
- Diabetes and Obesity Research
- Human Oncostatin M and Mouse LIF Support Mouse ES Cell Pluripotency & Germline Competency
- ICC / IHC Images: LIF
- IL-6 Family
- Megakaryocytes
- Mouse Obesity Antibody Array
- Obesity
- Reproduction
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