| 货号 | BAF4599 |
| 别名 | CAP1; channel-activating protease 1; EC 3.4.21; EC 3.4.21.-; EC 3.4.21.120; prostasin; protease, serine, 8; Prss8; Serine protease 8 |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human Prostasin/Prss8 in Western blots. In Western blots, approximately 10% cross‑reactivity with recombinant mouse Prostasin is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 5652 (Human); 76560 (Mouse) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Chinese hamster ovary cell line CHO-derived recombinant human Prostasin/Prss8 Ala33-Gly319 Accession # Q16651 |
| 生物活性 | Human |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Prostasin, also known as channel activating protease 1, is a serine protease with trypsin-like substrate specificity. The preproenzyme possesses a C-terminal membrane-spanning domain that can be proteolytically processed to generate a secreted form of the enzyme. It is highly expressed in the prostate gland, and is also found at lower levels in the lung, kidney, liver, salivary gland, and pancreas. The peptidase activity of prostasin is involved in the regulation of epithelial sodium channels. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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