货号 | BAF2427 |
别名 | FIL1- theta; FKSG75; IL1F10; IL-1HY2; interleukin 1 family, member 10 (theta); UNQ6119/PRO20041 | 全称 | Interleukin 1 Family Member 10 |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects human IL‑38/IL‑1F10 in Western blots. In Western blots, approximately 5% cross‑reactivity with recombinant human (rh) IL-1ra and rhIL-1F5 is observed and less than 1% cross-reactivity with rhIL-1 alpha, rhIL-18, rhIL-1F6, rhIL-1F7, rhIL-1F8, and rhIL-1F9 is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 84639 (Human); 215274 (Mouse) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist. | |
纯化方式 | Antigen Affinity-purified |
免疫原 | E. coli-derived recombinant human IL‑38/IL‑1F10 Cys2-Trp152 Accession # Q8WWZ1 |
生物活性 | Human |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | Human Il-38/IL-1F10 is a secreted cytokine belonging to the IL-1family. It is synthesized as a 152 amino acid mature protein that lacksan identifiable signal sequence. It binds to soluble IL-1 R1. HumanIL-1F10 shares 82% aa sequence identity with mouse IL-1F10. HumanIL-1F10 also shares 39% and 27% aa sequence identity with IL-1ra andIL-1 beta, respectively. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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