货号 | BAF1895 |
别名 | 9.5S alpha-1-glycoprotein; amyloid P component, serum; APCS; MGC88159; PTX2; PTX2serum amyloid P-component; SAP; SAPpentaxin-related | 全称 | Serum Amyloid P Component |
反应种属 | Rat |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects rat Pentraxin 2/SAP in Western blots. In Western blots, approximately 20% cross‑reactivity with recombinant human PTX2 and recombinant mouse PTX2 is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 325 (Human); 20219 (Mouse); 29339 (Rat) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant rat Pentraxin 2/SAP Gln21-Ser228 Accession # P23680 |
生物活性 | Rat |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | Pentraxin or Pentraxin 2 (PTX2), also known as Serum Amyloid P component (SAP), is a secreted serum glycoprotein belonging to the pentraxin superfamily. Pentraxins have a characteristic pentagonal discoid arrangement of five non-covalently bound subunits and bind a variety of molecules in a calcium- dependent lectin-like manner through a pattern-recognition-binding site. PTX2 is a major acute-phase protein and may function as an opsonin for a variety of ligands. PTX2 also associates ubiquitously with all amyloid deposits implicated in diseases including Alzheimers and prion diseases, type 2 diabetes and various systemic amyloidoses. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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