| 货号 | BAF844 |
| 别名 | Colorectal cancer suppressor; CRC18; CRCR1; deleted in colorectal cancer protein; deleted in colorectal carcinoma; IGDCC1colorectal tumor suppressor; Immunoglobulin superfamily DCC subclass member 1; immunoglobulin superfamily, DCC subclass, member 1; netrin receptor DCC; Tumor suppressor protein DCC | 全称 | Deleted in Colorectal Cancer |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects mouse DCC in Western blots. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 1630 (Human); 13176 (Mouse) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse DCC Met1-Asn1097 Accession # P70211 |
| 生物活性 | Mouse |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Deleted in colorectal cancer (DCC) encodes a typeI transmembrane glycoprotein that belongs to the immunoglobulin superfamily. Two forms of the protein (the long and short isoforms) are produced from the same gene by the use of alternative initiation sites. A third isoform that is produced by alternative splicing is expressed only in the embryo. The extracellular domain of mouse DCC shares 97% and 99% amino acid sequence identity with human and rat DCC extracellular domains, respectively. DCC is a receptor for the Netrin family axon guidance molecules. DCC functions primarily in axon attraction, but is also a coreceptor with UNC5 receptors for axon repulsion. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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