| 货号 | BAF783 |
| 描述 | For ELISA the Antibody Pairs information：Capture antibody：MAB783；Detection antibody：BAF783; and protein: 783-CL-050 |
| 别名 | CD27-L; CD27LCD27 ligand; CD27LG; CD70 molecule; CD70; Ki-24 antigen; surface antigen CD70; TNFSF7; TNFSF7CD70 antigen; tumor necrosis factor (ligand) superfamily, member 7; Tumor necrosis factor ligand superfamily member 7 |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL) ELISA Capture (Matched Antibody Pair)(2-8 µg/mL ) ELISA Detection (Matched Antibody Pair)(0.1-0.4 µg/mL ) ELISA Standard ( ) |
| 目标/特异性 | Detects mouse CD27 Ligand/TNFSF7 in ELISAs and Western blots. In sandwich immunoassays, less than 0.1% cross‑reactivity with recombinant human CD27 Ligand, recombinant mouse (rm) CD30 Ligand, and rmCD40 Ligand is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL ELISA Capture (Matched Antibody Pair): 2-8 µg/mL ELISA Detection (Matched Antibody Pair): 0.1-0.4 µg/mL ELISA Standard : |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 970 (Human); 21948 (Mouse) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse CD27 Ligand/TNFSF7 Gln47-Pro195 Accession # O55237 |
| 生物活性 | Mouse |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | CD27 Ligand, also known as CD70 and TNFSF7, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF). CD27 Ligand expression is induced by antigen-receptor activation in B cells. CD27/TNFRSF7 is expressed on natural killer (NK) cells and subsets of T and B cells. CD27 ligation on NK cells induces proliferation and IFN production. CD27 ligation on T cells provides a co-stimulatory signal required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD27 ligation on B cells inhibits terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
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