货号 | BAF772 |
别名 | 5F7; basigin (Ok blood group); Basigin; BSG; CD147 antigen; CD147; Collagenase stimulatory factor; EMMPRINTCSF; Extracellular matrix metalloproteinase inducer; Leukocyte activation antigen M6; M6; OK blood group antigen; OK; Tumor cell-derived collagenase stimulatory factor | 全称 | Extracellular Matrix Metalloproteinase Inducer |
反应种属 | Mouse |
应用 | Western Blot(0.1 µg/mL) Flow Cytometry(2.5 µg/106cells) |
目标/特异性 | Detects mouse EMMPRIN in Western blots. In Western blots, less than 1% cross‑reactivity with recombinant human EMMPRIN is observed. |
使用方法 | Western Blot: 0.1 µg/mL Flow Cytometry: 2.5 µg/106cells |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 682 (Human); 12215 (Mouse) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse EMMPRIN/CD147 Ala22-Arg209 Accession # NP_001070652 |
生物活性 | Mouse |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | The name EMMPRIN reflects this proteins extracellular metalloproteinase inducer activity. It is a cell surface protein with two extracellular Ig domains, a transmembrane domain, and a cytoplasmic domain. Its expression is often elevated in human tumor cells, which in turn promotes MMP-1, MMP-2 and MMP-3 production in melanoma cells and MMP-2 and MMP-9 production in breast cancer cells. It interacts with several types of molecules such as integrins, caveolin-1 and MCT1. TRA-1-85 is an epitope within EMMPRIN. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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