货号 | BAF747 |
别名 | CD127 antigen; CD127; CD127ILRA; CDW127; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL7R; IL7RA; IL-7RA; IL-7R-alpha; interleukin 7 receptor alpha chain; interleukin 7 receptor isoform H5-6; interleukin 7 receptor; interleukin-7 receptor subunit alpha | 全称 | Interleukin 7 Receptor alpha |
反应种属 | Mouse |
应用 | Western Blot(0.1 µg/mL) Flow Cytometry(2.5 µg/106cells) |
目标/特异性 | Detects mouse IL‑7 R alpha /CD127 extracellular domain in Western blots. In Western blots, no cross-reactivity with recombinant human IL-7 R is observed. |
使用方法 | Western Blot: 0.1 µg/mL Flow Cytometry: 2.5 µg/106cells |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 3575 (Human); 16197 (Mouse); 294797 (Rat) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse IL‑7 R alpha /CD127 Glu21-Asp239 Accession # P16872 |
生物活性 | Mouse |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | The biological effects of IL-7 are mediated by the binding of IL-7 to the specific cell surface receptor complex. The functional high-affinity IL-7 receptor (IL-7 R) comprises the IL-7 R alpha chain in association with the common gamma chain (gamma c). Both IL-7 R alpha and gamma c are members of the hematopoietin receptor superfamily. Human and mouse IL-7 R alpha show 64% amino acid sequence identity. IL-7 R alpha transcripts were observed in murine spleen, thymus, fetal liver, developing T cells, B cells, mature T cells and bone marrow-derived macrophages. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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