| 货号 | BAF733 |
| 别名 | desert hedgehog (Drosophila) homolog; desert hedgehog homolog; desert hedgehog protein; desert hedgehog; DHH; HHG-3MGC35145 |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL) Immunohistochemistry(5-15 µg/mL) |
| 目标/特异性 | Detects mouse Desert Hedgehog/Dhh N-Terminus in Western blots. In Western blots, approximately 5% cross-reactivity with recombinant mouse (rm) Shh N-terminal peptide is observed and less than 1% cross-reactivity with recombinant human Dhh C-terminal peptide, rmIhh C‑terminal peptide, and rmShh C‑terminal peptide is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL Immunohistochemistry: 5-15 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 50846 (Human); 13363 (Mouse) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant mouse Desert Hedgehog/Dhh aa 23-198 |
| 生物活性 | Mouse |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Dhh regulates testis development and spermatogenesis via interaction of its N-terminal domain with the receptors Patched and Patched-2. Hedgehog proteins are secreted as precursor molecules that undergo autocatalytic internal cleavage to yield an N-terminal domain that has signaling activity and a C-terminal domain that is active in precursor processing. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
|