| 货号 | BAF719 |
| 别名 | NOG; noggin; SYM1; symphalangism 1 (proximal); synostoses (multiple) syndrome 1; SYNS1 |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects mouse Noggin in Western blots. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 9241 (Human); 18121 (Mouse) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse Noggin Leu20-Cys232 Accession # P97466 |
| 生物活性 | Mouse |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Noggin is a 232 amino acid (aa), ~31 kDa homodimer-forming glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Noggin is expressed in defined areas during development and in the adult central nervous system and peripheral tissues such as lung, skeletal muscle, and skin. It is important for neural tube, somite and cardiomyocyte growth and patterning, and for limiting chondrocyte growth. Noggin is secreted but probably remains close to the cell surface due to its binding of heparin-containing proteoglycans. Mature human, mouse, and rat Noggin share 99% aa sequence identity. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
|