| 货号 | BAF5728 |
| 别名 | GFRAL; GRAL | 全称 | Glial Cell line-derived Neurotrophic Factor Receptor alpha-like |
| 反应种属 | Mouse |
| 应用 | Western Blot() |
| 目标/特异性 | Detects mouse GFR alpha -like in Western blots. In Western blots, less than 1% cross-reactivity with recombinant mouse (rm) GFR alpha -3 and rmGFR alpha -4 is observed. |
| 使用方法 | Western Blot |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 389400 (Human); 404194 (Mouse); 501023 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Chinese hamster ovary cell line CHO-derived recombinant mouse GFR alpha -like isoform A Gln20-Gly349 Accession # Q6SJE0 |
| 生物活性 | Mouse |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | GFR alpha-like (GDNF receptor-alpha-like) is a predicted 26 and 44 kDa glycoprotein and distant member of the GDNFR family of proteins. It is expressed on both fetal and adult neurons of the CNS, and would appear to function as an anti-apoptotic molecule during neuronal stress. Mature mouse GFR alpha-like is a 374 amino acid (aa) type I transmembrane protein. It contains a 330 aa extracellular region that shows a Gas1 domain (aa 131-210), and a 23 aa cytoplasmic tail. There is one splice variant that is likely soluble and shows a four aa substitution for aa 235-393. Over aa 20-349, mouse GFR alpha-like shares 72% aa identity with human GFR alpha-like. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
|