| 货号 | BAF5160 |
| 别名 | Alkaline sphingomyelin phosphodiesterase; alkaline sphingomyelinase; Alk-SMase; EC 3.1.4.12; ectonucleotide pyrophosphatase/phosphodiesterase 7; ectonucleotide pyrophosphatase/phosphodiesterase family member 7; E-NPP 7; Intestinal alkaline sphingomyelinase; MGC50179; NPP7; NPP-7 | 全称 | Ectonucleotide Pyrophosphatase/Phosphodiesterase 7 |
| 反应种属 | Mouse |
| 应用 | Western Blot() |
| 目标/特异性 | Detects mouse ENPP‑7/Alk‑SMase in Western blots. In Western blots, approximately 50% cross‑reactivity with recombinant human ENPP-7 is observed. |
| 使用方法 | Western Blot |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 339221 (Human); 238011 (Mouse); 303729 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse ENPP‑7/Alk‑SMase Ala22-Gln421 Accession # NP_001025462 |
| 生物活性 | Mouse |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | ENPP-7 (ectonucleotide pyrophosphatase/phosphodiesterase 7), also known as alkaline sphingomyelinase (alk-SMase) is a 60 kDa GPI-linked membrane glycoprotein expressed in the intestines and in human bile. It shares 30% - 36% homology with the NPP family, but is unrelated to neutral or acid SMase. ENPP-7 hydrolyzes dietary sphingomyelin to form ceramide and phosphorylcholine, and may also hydrolyze and inactivate platelet-activating factor (PAF). It is downregulated in some human colorectal carcinomas. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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