| 货号 | BAF5049 |
| 别名 | 5T4 oncofetal trophoblast glycoprotein; 5T4 oncotrophoblast glycoprotein; 5T4AG; 5T4-AG; 5T4M6P1,5T4 oncofetal antigen; M6P1; TPBG; trophoblast glycoprotein | 全称 | Oncofetal Antigen/Trophoblast Glycoprotein |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects mouse 5T4 in Western blots. In Western blots, approximately 5% cross-reactivity with recombinant human 5T4 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 7162 (Human); 21983 (Mouse); 83684 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse 5T4 Ser30-Ser361 Accession # AAH58198 |
| 生物活性 | Mouse |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | 5T4 (oncofetal antigen 5T4; also TPBG and trophoblast glycoprotein) is a member of the LRR family of proteins. It is expressed on trophoblasts, tumor cells, ovarian cuboidal epithelium and embryonic stem cells, and impacts cell adhesion and motility. Human 5T4 is a 72kD glycoprotein. The human 5T4 cDNA encodes a type I transmembrane protein precursor that is 420 amino acids (aa) in length. It contains a 324 aa extracellular region (aa 32 - 355) that shows one Ser-rich region followed by seven Leu-rich repeats (aa 90 - 355). Over aa 31 - 355, human 5T4 shares 81% and 85% aa identity with mouse and canine 5T4, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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