| 货号 | BAF474 |
| 别名 | CD210 antigen; CDw210a; HIL-10R; IBD28; IL-10 receptor subunit alpha; IL-10R subunit 1; IL-10R1; IL10RA; IL-10RA; IL10RIL-10R subunit alpha; interleukin 10 receptor, alpha; interleukin-10 receptor alpha chain; Interleukin-10 receptor subunit 1; interleukin-10 receptor subunit alpha | 全称 | Interleukin 10 Receptor alpha |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects mouse IL-10 R alpha in Western blots. In Western blots (under non-reducing and reducing conditions), less than 25% cross-reactivity with recombinant human IL-10 sR alpha is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3587 (Human); 16154 (Mouse) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse IL‑10 R alpha Thr24-Asn238 ( Lys188Arg and Glu222Gly) Accession # Q61727 |
| 生物活性 | Mouse |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Interleukin-10 Receptor alpha (IL-10 R?), also known as IL-10 R1, is a transmembrane ligand-specific component of the IL-10 receptor complex. It associates with IL-10 R beta to mediate the effects of IL-10 in the control of microbial infections, allergic and autoimmune inflammation, and cancer. IL-10 R beta also associates with IL-20 R alpha, IL-22 R alpha, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29. Immunosuppressive signal transduction through the IL-10 receptor complex can be inhibited by activation of TLR2, 4, or 9, enabling strengthened immune responses during infection. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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