| 货号 | BAF4464 |
| 别名 | ATPDase; CD39 antigen-like 3; CD39L3; CD39L3EC 3.6.1.5; CD39-like 3; EC 3.6.1; Ecto-apyrase 3; Ecto-ATP diphosphohydrolase 3; Ecto-ATPase 3; Ecto-ATPDase 3; ectonucleoside triphosphate diphosphohydrolase 3; ENTPD3; FLJ93839; HB6; HB6NTPDase 3; NTPDase-3 | 全称 | Ecto-Nucleoside Triphosphate Diphosphohydrolase 3 |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects mouse CD39L3/ENTPD3 in Western blots. In Western blots, approximately 35% cross-reactivity with recombinant human CD39L3 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 956 (Human); 215446 (Mouse); 316077 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Chinese hamster ovary cell line CHO-derived recombinant mouse CD39L3/ENTPD3 Gln44-Pro485 Accession # AAH79871 |
| 生物活性 | Mouse |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | CD39L3, or ectonucleoside triphosphate diphosphohydrolase-3 (NTPDase-3), is an integral membrane protein with an extracellular catalytic domain. rhCD39L3 was expressed as a protein lacking its N- and C-terminal transmembrane domains, resulting in the secretion of the soluble rhCD39L3 ectodomain. CD39L3 hydrolyzes the b- and g-phosphate groups of nucleotides, preferring ATP, ADP, UTP, and UDP as substrates. Through its hydrolysis of extracellular nuceotides, CD39L3 is important for the regulation of purinergic signaling. The enzyme is expressed at its highest levels in brain, pancreas, spleen, and prostate tissues. In the brain, CD39L3 may play a role in the regulation of feeding, sleep, and other behaviors. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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