货号 | BAF4388 |
别名 | FNDC6; DIRS1; FNDC6; IL-20R2; IL20RB interleukin 20 receptor beta; IL20RB; MGC34923 | 全称 | Interleukin 20 Receptor beta |
反应种属 | Mouse |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects mouse IL-20 R beta in Western blots. In Western blots, approximately 25% cross-reactivity with recombinant human IL-20 R beta is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 53833 (Human); 213208 (Mouse) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse IL‑20 R beta Asp14-Asn215 Accession # NP_001032323 |
生物活性 | Mouse |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | IL-20 R alpha (or IL-20 R1) and IL-20 R beta (or IL-20 R2) belong to the class II cytokine receptor family. They form multiple heterodimeric signaling complexes that mediate IL-10 family class II cytokine signals. IL-20 R alpha heterodimerizes with IL-20 R beta to form the functional receptor for IL-19, IL-20 and IL-24. IL-20 R alpha also heterodimerizes with IL-10 R beta to form a functional receptor complex for IL-26, while IL-20 R beta heterodimerizes with IL-22 R to form functional IL-20 and IL-24 receptors. The IL-20 receptors are thought to mediate a number of physiological functions including apoptosis, hematopoiesis, and anti-tumor activities. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
|