| 货号 | BAF3535 |
| 别名 | Ecalectin; GAL9; gal-9; galectin 9; galectin-9; HUAT; lectin, galactoside-binding, soluble, 9; LGALS9; LGALS9A; MGC117375; MGC125973; MGC125974; Tumor antigen HOM-HD-21; urate transporter/channel protein |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects mouse Galectin-9 in Western blots. In this format, less than 1% cross-reactivity with recombinant human (rh) Galectin‑2, rhGalectin‑8, recombinant mouse (rm) Galectin-1, rmGalectin-3, rmGalectin-4, and rmGalectin-7 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3965 (Human); 16859 (Mouse) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Influence of galectin-9/Tim-3 interaction on herpes simplex virus-1 latency. | |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant mouse Galectin‑9 short isoform Ala2-Thr353; aa148-178 deleted Accession # O08573 |
| 生物活性 | Mouse |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Galectin-9, also known as Ecalectin, belongs to the Galectin family(S-type lectins) of galactoside-binding proteins. It is a 36 - 39 kDaprotein that lacks a secretion signal sequence, but can be secreted bya non-classical pathway. Galectin-9 is a tandem-repeat Galectin withtwo Galectin domains joined by a linker region. Two alternative splicedvariants, a short and a long isoform, exist. Galectin-9 short isoformis expressed in a variety of tissues and cells, including fibroblasts,hepatocytes, endothelial cells and astrocytes. The long isoform,however, is expressed primarily in the intestine. Galectin-9 bindsTIM-3 on Th1 cells, inducing apoptosis. Mouse Galectin-9 shares 69% and85% amino acid sequence identity with human and rat Galectin-9,respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
|