| 货号 | BAF3007 |
| 别名 | B and T lymphocyte associated; B and T lymphocyte attenuator; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; BTLA1; CD272 antigen; CD272; FLJ16065; MGC129743 | 全称 | B- And T-Lymphocyte Attenuator |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects mouse BTLA in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human BTLA is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 151888 (Human); 208154 (Mouse) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse BTLA Glu30-Gly176 (Pro41Glu, Thr45Asn, Thr47Lys, Gln52His, Arg55Trp, Gln63Glu, Cys85Trp) Accession # Q32MV9 |
| 生物活性 | Mouse |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | BTLA (B- and T-lymphocyte attenuator; CD272) is a transmembrane immunoregulatory glycoprotein that is expressed on T cells, B cells, macrophages, dendritic cells, and NK cells. Its expression is low in naïve T cells and increases during antigen-specific induction of anergy. In B cells, BTLA expression is highest in mature naïve cells. BTLA binds to HVEM and negatively regulates homeostasis and inflammatory activation of CD8+ memory T cells and gamma/delta T cells. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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