| 货号 | BAF2950 |
| 别名 | CD371; CLEC12A; CLL1; CLL-1; C-type lectin domain family 12, member A; DCAL-2; MICL | 全称 | Myeloid Inhibitory C-type Lectin-like Receptor |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects mouse MICL/CLEC12A in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human MICL is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 160364 (Human); 232413 (Mouse) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse MICL/CLEC12A Thr67-Arg267 Accession # NP_808354 |
| 生物活性 | Mouse |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | MICL is a member of the group V subfamily of the C-type lectin-like family of molecules. It is found on the cell surface, contains an ITIM (immunoreceptor tyrosine-based inhibitory motif) in its cytoplasmic domain, and is N-glycosylated. Expression of MICL is restricted to granulocytes and monocytes, and it may function as a negative regulator of these cell types. At least three isoforms of MICL are generated by alternative splicing, including one that lacks the transmembrane domain. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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