货号 | BAF2948 |
别名 | MGC111216; PIG4; SAA; SAA1; SAA2; serum amyloid A protein; serum amyloid A1; TP53I4; tumor protein p53 inducible protein 4 |
反应种属 | Mouse |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects mouse Serum Amyloid A1 in Western blots. In Western blots, approximately 5% cross-reactivity with recombinant human Serum Amyloid A1 is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 6288 (Human); 20208 (Mouse) |
纯化方式 | Antigen Affinity-purified |
免疫原 | E. coli-derived recombinant mouse Serum Amyloid A1 Gly20-Tyr122 Accession # P05366 |
生物活性 | Mouse |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | Mouse Serum Amyloid A1 (SAA1) is a multifunctional apolipoprotein produced by hepatocytes in response to proinflammatory cytokines. It is secreted as a 12 kDa, 103 amino acid (aa), nonglycosylated polypeptide and circulates as part of the HDL complex. The SAA1 gene is one of three SAA genes in mouse, and, based on human, is likely to be allelic. The SAA1 gene product differs from the SAA2 gene product by only nine amino acids. In human, circulating SAA1 shows multiple proteolytically-generated isoforms, with anywhere from one to three amino acids being cleaved from either the N- or C-terminus. The same situation may exist in mouse. The amino acid sequence of mature mouse SAA1 is 72%, 72%, 67% and 74% identical to mature human, rabbit, equine and hamster SAA1, respectively. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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