货号 | BAF2568 |
别名 | EPIMepimorphin; EPM; STX2; STX2AMGC51014; STX2Bsyntaxin-2; STX2CEpimorphin; Syntaxin 2 |
反应种属 | Mouse |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects mouse Epimorphin/Syntaxin 2 in Western blots. In Western blots, approximately 40% cross‑reactivity with recombinant human Epimorphin is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 2054 (Human); 13852 (Mouse) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Overexpression of extracellular epimorphin leads to impaired epidermal differentiation in HaCaT keratinocytes. | |
纯化方式 | Antigen Affinity-purified |
免疫原 | E. coli-derived recombinant mouse Epimorphin/Syntaxin 2 Met1-Arg189 Accession # Q00262 |
生物活性 | Mouse |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | Epimorphin is a 31-to 34-kDa member of the Syntaxin family of secretory vesicle-docking proteins. It is a type IV transmembrane protein, suggesting it is membrane-anchored at the C-terminus with an N-terminal cytoplasmic tail. It is also suggested to be present on the cell surface. The molecule has two alpha-helical coiled-coil motifs that contribute to dimeric and tetrameric associations. Epimorphin is associated with branching morphogenesis. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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