货号 | BAF2500 |
别名 | Adipocyte-derived leucine aminopeptidase; A-LAP; A-LAPALAP; Aminopeptidase PILS; ARTS1; ARTS1aminopeptidase regulator of TNFR1 shedding; ARTS-1PILSAP; EC 3.4.11; EC 3.4.11.-; EC 3.4.11.1; endoplasmic reticulum aminopeptidase 1; endoplasmic reticulum aminopeptidase associated with antigen processing; ERAAP1; ERAP1; KIAA0525APPILS; PILS-AP; PILS-APERAAP; Puromycin-insensitive leucyl-specific aminopeptidase; Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator | 全称 | Aminopeptidase Puromycin-insensitive Leucyl-specific |
反应种属 | Mouse |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects mouse Aminopeptidase PILS/ARTS1 in Western blots. In Western blots, approximately 40% cross-reactivity with recombinant human ARTS1 is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 51752 (Human); 80898 (Mouse) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse Aminopeptidase PILS/ARTS1 Ser27-Leu930 Accession # NP_109636 |
生物活性 | Mouse |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | The name of Aminopetidase PILS (Puromycin-insensitive Leucyl-specific) describes the two basic properties of this zinc metalloproteinase in vitro. Also known as ALAP (Adipocyte-derived Leucine Aminopeptidase), Aminopeptidase regulator of TNFR1 shedding 1 (ARTS1), and ER Aminopeptidase ERAP1 or ERAAP, it is encoded by the ARTS1 gene. Aminopeptidase PILS is thought to regulate antigen presentation, promote TNFR1 and IL-6 R ectodomain shedding, and may be associated with hypertension. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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