概述货号 | BAF2434 |
别名 | a disintegrin and metalloprotease 33; a disintegrin and metalloproteinase domain 33; ADAM 33; ADAM metallopeptidase domain 33; C20orf153; chromosome 20 open reading frame 153; disintegrin and metalloproteinase domain-containing protein 33; disintegrin and reprolysin metalloproteinase family protein; dJ964F7.1; DKFZp434K0521; EC 3.4.24.-; FLJ35308; FLJ36751; MGC149823; MGC71889 |
全称 | A Disintegrin and Metalloproteinase Domain 33 | 反应种属 | Mouse |
应用 | Western Blot(0.1 µg/mL)
|
目标/特异性 | Detects mouse ADAM33 Ectodomain in Western blots. In Western blots, less than 5% cross-reactivity with recombinant human (rh) ADAM8, rhADAM17, rhADAM33, recombinant mouse (rm) ADAM9, rmADAM10, and rmADAM15 is observed. |
使用方法 | Western Blot: 0.1 µg/mL
|
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 | |
性能供应商 | R&D Systems |
Entrez Gene IDs | 80332 (Human); 110751 (Mouse) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse ADAM33 Ectodomain |
生物活性 | Mouse |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | Members of the ADAM or MDC (Metalloprotease, Disintegrin, Cysteine-rich) family contain pro, metalloprotease-like, disintegrin-like, cysteine-rich, transmembrane and cytoplasmic domains. They play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. Over 30 members have been identified and about half of them are active metalloproteases such as ADAM8, 9, 10, 12 and 17/TACE. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 | - Metalloproteases and Regulators
- Mini-review: ADAMs
|