货号 | BAF1885 |
别名 | T Cell immunoglobulin and mucin domain protein 2; Tim2 | 全称 | T Cell Immunoglobulin Mucin-2 |
反应种属 | Mouse |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects mouse TIM-2 in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human TIM-1 and recombinant mouse TIM-3 is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 171284 (Mouse) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse TIM‑2 Met1-Asn229 Accession # NP_599010 |
生物活性 | Mouse |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | TIM-2 is a type I membrane protein and is a member of the TIM protein family. TIM-2 has an immunoglobulin variable region-like domain followed by a mucin-like domain in its extracellular region.This protein family is characterized by their conserved immunoglobulin and mucin domains, as well as by their expression on activated T cells. TIM-2 is a receptor for Semaphorin 4A, which is expressed on dendritic cells and B cells. Semaphorin 4A has been shown to enhance T cell activation. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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