货号 | BAF1797 |
别名 | CD204 antigen; CD204; Macrophage acetylated LDL receptor I and II; macrophage scavenger receptor 1; macrophage scavenger receptor type III; MSR1; phSR1; phSR2; SCARA1; SCARA1macrophage scavenger receptor types I and II; Scavenger receptor class A member 1; scavenger receptor class A, member 1; SR-A | 全称 | Macrophage Scavenger Receptor Types I and II |
反应种属 | Mouse |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects mouse SR‑AI/MSR in Western blots. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 4481 (Human); 20288 (Mouse); 25073 (Rat) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse SR‑AI/MSR Trp83-Ser458 Accession # P30204 |
生物活性 | Mouse |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | The scavenger receptor (SR) family is a group of membrane receptors that share the common ability to bind and internalize modified forms of low-density lipoproteins (mLDL). The three SR-A alternatively spliced isoforms (I, II, and III) and a structurally similar protein, MARCO, make up the A class of homotrimeric, type II membrane proteins. SR-AI has an N-terminal cytoplasmic domain, transmembrane domain, spacer domain, a-helical coiled coil domain, collagen-like domain, and C-terminal cysteine-rich domain. SR-As are expressed by most tissue macrophages and dendritic cells. SR-As bind a broad range of polyanionic ligands and therefore have been implicated in many physiological and pathophysiological functions. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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