Influenza A Virus H1N1 Neuraminidase Biot Aff Pur PAb (50 UG)
货号：
BAF4858 基本售价：
5532.3 元 规格：
-
产品信息
概述| 货号 | BAF4858 |
| 别名 | NANH |
| 应用 | Western Blot(0.1 µg/mL)
|
| 目标/特异性 | Detects Influenza A Virus H1N1 Neuraminidase in Western blots. |
| 使用方法 | Western Blot: 0.1 µg/mL
|
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant Influenza A Virus H1N1 Neuraminidase |
| 生物活性 | Influenza A Virus H1N1 |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. HA is a lectin that binds sialic acid on host cell membrane. Neuraminidase is a sialic acid hydrolase that specifically clips off terminally located sialic acid on host cell surface. The two proteins are essential for infectious cycle of influenza virus. During initial infection, an influenza virus will hold onto an epithelial cell through HA-sialic acid interaction. At the end of an infectious cycle, the neuraminidase will cleave the sialic acid on the host cell membrane, releasing the newly formed viral particle from the HA-sialic acid bondage. The neuraminidase activity is also thought to help the virus penetrate mucus. Nine subtypes of NA have been identified, all of which are tetrameric and share a common structure consisting of a globular head, a thin stalk region, and a small hydrophobic region that anchors the protein in the virus membrane. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Glycobiology-related Enzymes
- Infectious Diseases
- Molecular Characterization of the Active 1918 Pandemic Flu Viral Neuraminidase
|
