货号 | BAF773 |
别名 | AF-1; AF-1interferon-gamma receptor beta chain precursor10IFNGT1Interferon gamma receptor accessory factor 1; IFGR2; IFN-gamma receptor 2; IFN-gamma-R2; IFNGR2; IFNGT1; interferon gamma receptor 2 (interferon gamma transducer 1); interferon gamma receptor 2; interferon gamma receptor accessory factor-1; interferon gamma receptor beta chain; Interferon gamma transducer 1 | 全称 | Interferon gamma Receptor 2 |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) Flow Cytometry(2.5 µg/106cells) |
目标/特异性 | Detects human IFN‑ gamma R2 in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human (rh) IFN-gamma RI and rhIL‑10 R beta is observed. |
使用方法 | Western Blot: 0.1 µg/mL Flow Cytometry: 0.25 µg/106cells |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 3460 (Human); 15980 (Mouse) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human IFN-gamma R2 Met1-Gln247 Accession # P38484 |
生物活性 | Human |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | The high-affinity IFN-gamma receptor complex is made up of two type I membrane proteins, IFN-gamma R1 and IFN-gamma R2. Both proteins are members of the type II cytokine receptor family. IFN-gamma R1 is the ligand-binding subunit that is necessary and sufficient for IFN-gamma binding and receptor internalization. IFN-gamma R2 is required for signaling but does not bind IFN-gamma by itself. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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Detection of IFN‑ gamma R2 in THP‑1 Human Cell Line by Flow Cytometry. THP‑1 human acute monocytic leukemia cell line was stained with Goat Anti-Human IFN‑ gamma R2 Biotinylated Antigen Affinity‑purified Polyclonal Antibody (Catalog # BAF773, filled histogram) or isotype control antibody (Catalog # BAF108, open histogram), followed by Streptavidin-Allophycocyanin (Catalog # F0050). |