| 货号 | BAF613 |
| 别名 | GDNF family receptor alpha 2; GDNF family receptor alpha-2; GDNF R alpha-2; GDNF receptor alpha-2; GDNF receptor beta; GDNFR-alpha-2; GDNFR-beta; GDNFRBRET ligand 2; GFRA2; GFR-alpha 2; GFR-alpha-2; glial cell line derived neurotrophic factor receptor, beta; Neurturin receptor alpha; NRTNR-alpha; NTNRA; NTNR-alpha; PI-linked cell-surface accessory protein; RETL2TGF-beta-related neurotrophic factor receptor 2; TGF-beta related neurotrophic factor receptor 2; TRN receptor, GPI-anchored; TRNR2NRTNR-ALPHA | 全称 | Glial Cell line-derived Neurotrophic Factor Receptor alpha 2 |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human GFR alpha ‑2/GDNF R alpha ‑2 in Western blots. In Western blot, approximately 25% cross-reactivity with recombinant mouse GFR-alpha 2 (under non-reducing conditions) is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 2675 (Human); 14586 (Mouse) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human GFR alpha ‑2/GDNF R alpha ‑2 Met1-Ser441 Accession # O00451 |
| 生物活性 | Human |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | GFR alpha -1, -2, -3, and -4 are GPI-anchored receptors that interact preferentially with the GDNF family ligands GDNF, Neurturin, Artemin, and Persephin, respectively. GFR alpha proteins initiate signaling in association with the receptor tyrosine kinase RET and by RET-independent pathways. GFR alpha-mediated signaling is instrumental in the differentiation, migration, and support of central and peripheral neurons. Alternative splicing generates multiple isoforms of GFR alpha proteins. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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