Human Plexin B2 Biotinylated Affinity Purified PAb (50 UG)
货号：
BAF5329 基本售价：
5532.3 元 规格：
-
产品信息
概述| 货号 | BAF5329 |
| 别名 | MM1; MM1KIAA0315dJ402G11.3; Nbla00445; PLEXB2; plexin B2; plexin-B2; PLXNB2 |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL)
|
| 目标/特异性 | Detects human Plexin B2 in Western blots. In Western blots, less than 1% cross‑reactivity with recombinant human (rh) Plexin A4, rhPlexin B1, rhPlexin B3, rhPlexin C1, and rhPlexin D1 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL
|
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 23654 (Human); 140570 (Mouse); 315217 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Chinese hamster ovary cell line CHO-derived recombinant human Plexin B2 |
| 生物活性 | Human |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Plexin B2 is a 240 kDa member of the B subfamily, Plexin family of semaphorin receptors. It is expressed by cerebellar granule cells, neuroepithelium and chondrocytes and serves as a receptor for Sema4C. Mature human Plexin B2 is 1819 amino acid (aa) in length. It is a type I transmembrane (TM) glycoprotein that contains an 1178 aa extracellular domain (ECD) plus a 620 aa cytoplasmic region. The ECD contains one semaphorin domain (aa 20 - 466) and three IPT repeats (aa 803 - 1092). The ECD may be cleaved into two subunits, a 170 kDa alpha-chain (aa 20 - 1164) and an 80 kDa TM beta-chain that remain noncovalently-linked. Multiple splice variants may exist. One shows an alternate start site at Met1369, while a second shows a deletion of aa 67 - 638. Over aa 20 - 1160, human Plexin B2 is 82% aa identical to mouse Plexin B2. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - ICC / IHC Images: Plexin B2
- Semaphorins, Plexin Receptors, and Related Molecules
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