| 货号 | BAF5137 |
| 别名 | bone- and odontoblast-expressed gene 1; Bono1; FKSG28; FKSG40; FLJ24094; IGFBP-related protein 10; IGFBP-rP10; KAZALD1; Kazal-type serine peptidase inhibitor domain 1; Kazal-type serine protease inhibitor domain 1; kazal-type serine protease inhibitor domain-containing protein 1; novel kazal-type serine protease inhibitor domain and immunoglobulin domain containing protein; UNQ2945/PRO21184 | 全称 | Insulin-like Growth Factor Binding Protein Related Protein-10 |
| 反应种属 | Human |
| 应用 | Western Blot |
| 目标/特异性 | Detects human IGFBP-rP10 in Western blots. In Western blots, approximately 10% cross‑reactivity with recombinant mouse IGFBP-rP10 is observed. |
| 使用方法 | Western Blot |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 81621 (Human); 107250 (Mouse); 293997 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human IGFBP‑rP10 isoform 1 aa 31-304 Accession # Q96I82 |
| 生物活性 | Human |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF. ALS (Acid Labile Subunit) is a liver-derived protein that exists in a ternary complex with Insulin-like Growth Factor (IGF)-binding Protein-3 (IGFBP-3) or IGFBP-5, and either IGF-I or IGF-II. ALS increases the half-life of IGF/IGFBP complexes in circulation. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
|