| 货号 | BAF4358 |
| 别名 | EC 3.5.1; EC 3.5.1.-; FLJ35621; FLJ37491; S.cerevisiae, homolog) 2; SIR2L2; SIRT2; sirtuin 2; sirtuin type 2 | 全称 | Silent Mating Type Information Regulation 2 Homolog |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human Sirtuin 2/SIRT2 in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human SIRT1 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 22933 (Human); 64383 (Mouse); 361532 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Sirtuin 2/SIRT2 Ala2-Gln389 Accession # Q8IXJ6 |
| 生物活性 | Human |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Sirtuin 2, is a member of the class III histone deacetylases (HDACs) and has been implicated in many cellular processes that include histone deacetylation, gene silencing, chromosomal stability, and aging (3 - 4). The enzymatic activity of class III HDACs is nicotinamide adenine dinucleotide (NAD) dependent and insensitive to HDAC inhibitor trichostatin A. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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