货号 | BAF4336 |
别名 | CAP; CAPMGC111370; Cytoplasmic antiproteinase; deafness, autosomal recessive 91; DFNB91; Peptidase inhibitor 6; PI6; PI-6; PI6MSTP057; Placental thrombin inhibitor; protease inhibitor 6 (placental thrombin inhibitor); PTI; PTIDKFZp686I04222; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6; serpin B6; serpin peptidase inhibitor, clade B (ovalbumin), member 6; SPI3 |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects human Serpin B6 in Western blots. In Western blots, approximately 5% cross-reactivity with recombinant human (rh) Serpin B8 and rhSerpin B9 is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 5269 (Human); 20719 (Mouse); 291085 (Rat) |
纯化方式 | Antigen Affinity-purified |
免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Serpin B6 Asp2-Pro376 Accession # P35237 |
生物活性 | Human |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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