| 货号 | BAF4259 |
| 别名 | FLJ16691; paxillin; PXN |
| 反应种属 | Human/Mouse/Rat |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human Paxillin in Western blots. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 5829 (Human); 19303 (Mouse); 360820 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant human Paxillin Asn59-Ser274 Accession # P49023 |
| 生物活性 | Human, Mouse, Rat |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Paxillin is a 65 kDa cytoskeletal adaptor protein and member of the Paxillin family. Paxillin is found at the interface between actin filaments and the plasma membrane, and it localizes to focal adhesions, where it provides a platform for the integration and coordination of adhesion- and growth factor-related signals. Paxillin phosphorylation at tyrosines 31 and 118 is required for integrin-mediated cytoskeletal reorganization, and may play a role in the disassembly of focal adhesions and stress fibers during cellular transformation. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
|