| 货号 | BAF4189 |
| 别名 | activating receptor PILRbeta; Activating receptor PILR-beta; Cell surface receptor FDFACT; cell surface receptor FDFACT1; cell surface receptor FDFACT2; FDFACT; FDFACT1; FDFACT2; paired immunoglobin-like receptor beta; paired immunoglobin-like type 2 receptor beta; paired immunoglobulin-like receptor beta; paired immunoglobulin-like type 2 receptor beta; PILRB | 全称 | Paired-Ig-likeType 2 Receptor beta |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human PILR-beta in Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human PILR-alpha is observed and less than 5% cross-reactivity with recombinant mouse PILR-beta, rmPILR-alpha, and rmPILR-L is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 29990 (Human); 170741 (Mouse) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human PILR-beta isoform 1 Gln20-Ala189 Accession # Q9UKJ0 |
| 生物活性 | Human |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Mouse PILR-beta is a type I transmembrane (TM) glycoprotein involved in cell activation. It contains a positively charged TM domain that interacts with ITAM adaptor molecules and it is expressed on NK cells, macrophages, granulocytes, and dendritic cells. Its extracellular domain (ECD) shares 76% aa identity with the ECD of its paired inhibitory receptor, PIRL-alpha. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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