货号 | BAF4108 |
别名 | cancer susceptibility; FLJ25530; glial cell adhesion molecule; GlialCAM; hepaCAM; hepatic and glial cell adhesion molecule; hepatocyte cell adhesion molecule; Protein hepaCAM | 全称 | Hepatocyte Cell Adhesion Molecule |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects human HepaCAM in Western blots. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 220296 (Human) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human HepaCAM Val34-Tyr242 Accession # Q14CZ8 |
生物活性 | Human |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | HepaCAM (hepatocyte cell adhesion molecule) is a 75 kDa, type I transmembrane glycoprotein that belongs to the Ig-superfamily. It forms homodimers on the cell surface and promotes cell spreading and motility. Human HepaCAM is 382 aa in length. It contains a 206 aa extracellular domain (ECD) (aa 35-240) and a 152 aa cytoplasmic region. The ECD has two C2 Ig-like domains. There is one potential truncated isoform that shows an alternate start site at Met200. Over aa 34-242, human HepaCAM shares 99% and 98% aa sequence identity with mouse and dog HepaCAM, respectively. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
|