货号 | BAF4100 |
别名 | dipeptidyl peptidase 10; Dipeptidyl peptidase IV-related protein 3; dipeptidyl peptidase like protein 2; Dipeptidyl peptidase X; Dipeptidyl peptidase-like protein 2; dipeptidyl-peptidase 10 (non-functional); dipeptidyl-peptidase 10; DPL2; DPP X; DPPY; DPRP3; DPRP-3; DPRP3dipeptidylpeptidase 10; inactive dipeptidyl peptidase 10; KIAA1492 | 全称 | Dipeptidyl-peptidase 10 |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects human DPP10 in Western blots. In Western blots, less than 5% cross-reactivity with recombinant human (rh) DDP4 and rhDPP6 is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 57628 (Human); 269109 (Mouse); 363972 (Rat) |
纯化方式 | Antigen Affinity-purified |
免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant human DPP10 isoform 1 Leu56-Glu796 (Pro340Ala) Accession # NP_065919.2 |
生物活性 | Human |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | Dipeptidyl peptidase IV (DPPIV/CD26) is a serine exopeptidase that releases Xaa-Pro dipeptides from the N-terminus of proteins and peptides. It plays an important role in T-cell costimulation, chemokine biology, type II diabetes and tumor biology. There are at least 15 DPPIV-related human genes. Some function as enzymes, including DPP8, DPP9, fibroblast activation protein (FAP), prolyl endopeptidase (PREP), and N-acylaminoacyl-peptide hydrolase (APEH) while others (DPP6/DPPX and DPP10/DPRP3) may have lost their protease properties but acquired novel functions. For example, DPP6 is a critical component of neuronal A-type K+ channels. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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