Human Aminopeptidase N/CD13 Biotin Affinity Purified PAb (50 UG)【科瑞奥博】

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Human Aminopeptidase N/CD13 Biotin Affinity Purified PAb (50 UG)

货号： BAF3815 基本售价： 5532.3 元规格： -

产品信息

概述
货号	BAF3815
别名	alanyl (membrane) aminopeptidase; Alanyl aminopeptidase; Aminopeptidase M; aminopeptidase N; ANPEP; AP-M; APN; AP-N; CD13 antigen; CD13; CD13APN; EC 3.4.11; EC 3.4.11.2; gp150; LAP1; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; p150; PEPN; PEPNhAPN
反应种属	Human
应用	Western Blot(0.1 µg/mL) Flow Cytometry(2.5 µg/10⁶cells)
目标/特异性	Detects Aminopeptidase N/CD13 in Western blots. In Western blots, approximately 25% cross-reactivity with recombinant mouse APN is observed.
使用方法	Western Blot: 0.1 µg/mL Flow Cytometry: 2.5 µg/10⁶cells
来源	Reconstitute at 0.2 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	290 (Human); 16790 (Mouse)
纯化方式	Antigen Affinity-purified
免疫原	Mouse myeloma cell line NS0-derived recombinant human Aminopeptidase N/CD13 Lys69-Lys967 Accession # NP_001141
生物活性	Human
标记	Biotin
溶解方法	Reconstitute at 0.2 mg/mL in sterile PBS.
背景	The human ANPEP gene encodes aminopeptidase N (APN), which is also known as microsomal aminopeptiase, alanyl aminopeptidase, aminopeptidase M, CD13, or membrane protein p161 (1‑3). The deduced amino acid sequence of human APN consists of a short cytoplasmic tail (residues 2 to 8), a transmembrane region (residue 9 to 32), a Ser/Thr rich region and a zinc metalloprotease domain (residues 69 to 966). Widely expressed in many cells, tissues and species, APN cleaves the N-terminal amino acids from bioactive peptides, leading to their inactivation or degradation. The roles of APN in many fields, such as neuroscience, hematopoeitic cells, immune system, angiogenesis, cancer and viral infection, have been reviewed (3).
运输条件	Blue Ice
存放说明	-20℃
参考文献	Olsen, J. et al. (1988) FEBS Lett. 238:307. Look, A.T. et al. (1989) J. Clin. Invest. 83:1299. Turner, A.J. (2004) in Handbook of Proteolytic Enzymes (ed. Barrett, et al.) pp. 289, Academic Press, San Diego.

参考图片

Detection of Aminopeptidase N/CD13 in U937 Human Cell Line by Flow Cytometry. U937 human histiocytic lymphoma cell line was stained with Sheep Anti-Human Aminopeptidase N/CD13 Biotinylated Antigen Affinity‑purified Polyclonal Antibody (Catalog # BAF3815, filled histogram) or control antibody (Catalog # BAF020, open histogram), followed by Streptavidin-Phycoerythrin (Catalog # F0040).