| 货号 | BAF3526 |
| 别名 | GLI family zinc finger 2; GLI-Kruppel family member GLI2; glioma-associated oncogene family zinc finger 2; HPE9tax helper protein 1; oncogene GLI2; tax helper protein 2; Tax helper protein; tax-responsive element-2 holding protein; tax-responsive element-25-bp sequence binding protein; THP; THP1; THP2; zinc finger protein GLI2 | 全称 | GLI-Kruppel family member GLI2 |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) Immunocytochemistry(5-15 µg/mL) |
| 目标/特异性 | Detects human GLI-2 in Western blots. In Western blots, approximately 25% cross-reactivity with recombinant mouse GLI-2 is observed and 5% cross-reactivity with recombinant human (rh) GLI-1 and rhGLI-3 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL Immunocytochemistry: 5-15 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 2736 (Human); 14633 (Mouse); 304729 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant human GLI-2 Ala2-Glu91 Accession # BAA03568 |
| 生物活性 | Human |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | GLI family proteins are zinc finger transcription factors best known for regulating the expression of gene targets of Hedgehog (Hh) signaling. They share homology with the Drosophila Ci protein, which serves as a mediator of Hh responses in the fly. GLI3 functions primarily as a repressor of Hh target gene expression, while GLI-1 and GLI-2 are activators that promote Hh signaling. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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