| 货号 | BAF3455 |
| 别名 | GLI family zinc finger 1; glioma-associated oncogene family zinc finger 1; glioma-associated oncogene homolog 1 (zinc finger protein); Glioma-associated oncogene; GLIzinc finger protein GLI1; Oncogene GLI | 全称 | Glioma-Associated Oncogene Homolog 1 [Zinc Finger Protein] |
| 反应种属 | Human/Mouse |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human and mouse GLI-1 in Western blot. In Western blots, less than 1% cross-reactivity with recombinant mouse (rm) GLI-2 and rmGLI-3 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 2735 (Human); 14632 (Mouse); 140589 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant mouse GLI-1 Met1-Glu237 Accession # P47806 |
| 生物活性 | Human, Mouse |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | GLI-1 is a member of the Krupple family of zinc finger proteins. GLI-1 is activated by the sonic hedgehog pathway and influences transcription of a variety of target genes by binding to the consensus site 5’CGGGTGGTC3’. GLI-1 activation leads to cellular proliferation and anti-apoptotic activities based on target genes activated. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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