| 货号 | BAF3055 |
| 别名 | EC 2.7.10; EC 2.7.10.1; insulin receptor-related protein; insulin receptor-related receptor; IRR; IRRIR-related receptor | 全称 | Insulin Receptor-related Receptor |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human INSRR in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human INSR is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3645 (Human); 23920 (Mouse) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human INSRR Leu24-Leu923 Accession # P14616 |
| 生物活性 | Human |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | INSRR is a 175 kDa orphan receptor belonging to the insulin receptor subfamily of the receptor tyrosine kinase family. It is synthesized as a single chain type I transmembrane glycoprotein precursor and undergoes proteolytic processing to generate the mature disulfide linked alpha 2/ beta 2 tetrameric receptor. The alpha subunit is localized extracellularly while the transmembrane beta subunit contains an extracellular domain, a transmembrane segment and a cytoplasmic kinase domain. A ligand for INSRR has not yet been identified. The extracellular domain of human INSRR shares approximately 90% amino acid sequence homology with the mouse protein. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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